Abomi Nation is a roguelike mons RPG — essentially, an entire game built around a randomizer Nuzlocke. I think this is a pretty smart pairing — the biggest problem in mons games is that it’s infeasible for a single player to use more than a small fraction of the total roster, so by building the game around multiple playthroughs and randomizing your team each run, you get to appreciate a wider variety of mons than you would otherwise.
The Nuzlocke comparison is very apt, however, because the gameplay is otherwise nearly identical to Pokemon’s, with all of its flaws along for the ride.